Noticeably that although diffusely dispersed in the RPE layer, lipofuscin-like particles were prone to aggregate around cells of compromised integrity.
Therefore, we reasoned that reduced VASP expression in ATGL-deficient aortas might result in compromised integrity of the endothelial cell layer.
Recent evidence suggests that a compromised integrity of the blood brain barrier (BBB) results in a subsequent increase in BBB permeability which enables toxic soluble factors released either by host or parasite to cross this barrier and exert neurological effects.
These authors argue that SD results from a compromised architectonics of the cartilage growth plate of vertebral body, a compromised integrity of cells and matrix, and disbalance of proteoglycan/collagen ratio, which, all together, lead to the wedge-shaped deformity of vertebral bodies under mechanical loading.
This finding may be an isolated sign of blunt ocular trauma and a compromised integrity of the vitreolenticular interface should be strongly suspected.
Second, clinical recording procedures were fragmented still in pre-integration format, which compounded the workload challenge for providers and likely compromised integrity of the clinical information system, especially as a source of information for decision-making.
Compromised integrity of the ruminal epithelium can enable the transmigration of rumen microbes into portal circulation, leading to liver abscesses and an array of immunological responses [ 2].
Chartkov becomes a lucrative society portraitist, until awareness of wasted talents and compromised integrity provokes a psychological implosion.
By the early 1990s the compromised integrity of the FBI with respect to Bulger had become apparent to local and state police, who, along with the federal Drug Enforcement Administration, then launched a new investigation.
Thus, like women, female mice exhibit age-related fertility decline linked to oocyte-derived aneuploidy and compromised integrity of the molecular chromosomal "glue" known as cohesin (47, 48).
Here we demonstrate the strong impact of compromised epithelial integrity on normal and oncogenic Myc-driven proliferation in three-dimensional mammary epithelial organoid culture.
