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Patients with thyroid cancer may develop RP nodal metastases following surgery because of alteration of the lymph node drainage in a retrograde fashion [ 20- 23].
Moreover, cell contact stability was reported to be affected by COUP-TFI overexpression in fibroblast cells, most likely because of alteration of cell attachment proteins expression [ 45].
28– 31 Patients with DM are at greater risk of vertebral fractures, not only due to extraskeletal factors, such as predisposition to falls but also, because of alteration of bone quality and reduction of bone strength.
It is most likely that this occurs because of alteration of the principal MHC-binding residue for the insulin-reactive CD8 T cell epitope as shown in our previous study 21, in addition to the effects that may occur for the CD4 T cells in that model system.
The therapeutic use of albumin in hepatology dates back to the 1960s when it was thought that hypoalbuminemia had a prominent role in the pathogenesis of ascites, because of alteration of the balance between the forces of Starling in the intrahepatic microcirculation.
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Most notably, mutations in one of the genes encoding eIF5a lead to slower decapping of mRNAs, perhaps because of alteration to translation initiation and/or translation elongation (Zuk and Jacobson 1998; Saini et al. 2009).
Our data support the idea that M. tuberculosis strains of the W-Beijing genotype may have adapted to hostile environments, including exposure to anti-TB drugs, because of a succession of alterations of DNA repair enzymes.
The rest is amorphous, probably because of alteration by microbes during sedimentation.
In summary, carotenoids contents could be lower in crops because of alteration by humans of seed dispersal and seed dormancy.
The aggregation property is usually deregulated in the tumour cells because of alteration in the expression of different cell surface molecules (Sommers, 1996; Komatsu et al, 1997; Truant et al, 2003).
Because of alterations in cell adhesion and the acquisition of differentiation ability into the three germ cell layers, similar to mesenchymal cells, we next compared the expression patterns of EMT markers in RICs and normal HDFs by immunocytochemistry (Fig. 5f o).
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