Sentence examples for because of adaptation mutations from inspiring English sources

Interspecies transmission of the Env/9306 strain remains a risk to mammals because of adaptation mutations (5, 9 ) and is supported in this study by replication in ferrets and in human and swine tissues.

The importance of these Vero cell adaptation mutations in flavivirus vaccine design and development is discussed.

Recombinant viruses encoding various combinations of these Vero cell adaptation mutations did not demonstrate enhanced replication in Vero cells over that exhibited by the single mutations.

In contrast, human alleles of TRIM5α do not result in escape mutations, likely because of adaptation of the pathogen to the host (Rahm et al., 2013).

Understanding the genetic basis of evolutionary adaptation is limited by our ability to efficiently identify the genomic locations of adaptive mutations.

At the end of both adaptations, mutations accompanying the adaptations were tested for compensatory vs. noncompensatory status.

Maurer-Stroh S, Li Y, Bastien N et al. Potential human adaptation mutation of influenza A(H5N1) virus, Canada.

Our model predicts response patterns highlighting the interference of epitope and linked non-epitope loci with each other's evolution and function: Clonal interference limits functionality and speed of adaptation, because beneficial mutations are continuously lost in the competition between strains (Gerrish and Lenski 1998).

Development of a Comprehensive Genotype-to-Fitness Map of Adaptation-Driving Mutations in Yeast.

This result illustrates the dependence of the degree of adaptation on the mutation rate, as previously reported [42].

If the rate of beneficial mutations and their selective effects are constant across species, larger populations are expected to show higher rates of adaptation, both because they generate more mutations and selection is effective on a greater proportion of mutations [ 18, 46].