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Research on fatigue – which is also often mentioned as a very difficult and handicapping aspect of RA - was primarily included because of a hypothesis that fatigue would negatively impact on sexual activity.
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Because participants' awareness of a hypothesis may bias exposure reporting [ 39], we evaluated differences in beliefs about disease causation between cases and controls using the chi square test.
Or should we say this is clinical research because it involves the systematic testing of a hypothesis which is answered by collecting data on the patients' outcomes?
It bears noting that the rejection of a hypothesis does not automatically imply the refutation of an entire theory because hypotheses are usually sufficiently focused to test only one aspect of complex theories.
We included these covariates because of a priori hypotheses that these variables might be related to calorie estimation.
One-tail tests were performed for cell proliferation experiments because of a priori hypotheses regarding treatment effects (that is, inhibition for androgens and induction for antiandrogens).
However, these studies often focused on a subset of regions either because of a priori hypotheses or due to the limited coverage of the DNA methylation profiling technology used.
Covariates were included in models 1 4 because of a priori hypotheses that they could confound the relationship between our primary variables of interest and ln-radon concentration or based on the quasi-likelihood information criterion (Hardin and Hilbe 2013).
Because of a priori hypotheses about activations in the middle frontal gyrus and the rostral cingulate cortex, we also used regions of interest (ROIs) for the dorsal prefrontal cortex and the rostral cingulate cortex, derived from the results of the previous study by Rowe et al. (2008).
This was because one needed a hypothesis of how to apply the abstract demonstrative truths to observed facts ("Introduction" §7) — how to fit the fitnesses to actions so to speak — and this hypothesis itself was not deductively secure.
Results were compared between groups with 1-tailed tests because of a directionally specific hypothesis in favor of the tPA group.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com