Sentence examples for because mutants are available from inspiring English sources
Because mutants are available for a very limited number of genes, we focused on MO-mediated LOF, which is the most feasible way to assay the activity of the large 16p11.2 gene set.
Our choice of example protein was the Drosophila BicD because it is conserved up to humans, is involved in different cellular processes that act during different phases of the life cycle, and because null mutants are available that allow us to test the functions of phosphorylation in all these phases.
However, the functions of most mRNAs that localize to these structures in pattern formation or germ cell specification are unknown, because mutations affecting them are lethal, or because mutations block oogenesis before mature eggs that can be fertilized are formed, or because no mutants are available.
Vice versa, many highly conserved genes were essential according to the standard definition (experimentally essential) because no transposon mutants are available in either of the two comprehensive libraries [ 13, 14].
The physiological function of PsOep23 in vivo could not be clarified in this study, because no loss-of-function mutants are available.
Experiments to investigate the localisation of our NF1-AS reporter in mutants lacking different Ras proteins were also unsuccessful because the reporter does not localise in the Ax2 (and AX3) backgrounds where these mutants are available.
Because no loss-of-function mutants were available in the L er ecotype, we downregulated ARF2 and ARF6 mRNA levels via artificial miRNAs (amiR).
