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Because most clinical studies have been conducted using patients with the clear-cell subtype of RCC, their findings may not be applicable for the non clear-cell RCC subtypes, which differ molecularly as well as histologically [5].
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But most clinical studies using interventions intended to prevent early deliveries -- like better prenatal care, drugs that prevent contractions and hospitalization -- have failed.
This was a unique study because most clinical trials exclude patients with severe hypoglycemia.
This is an important question because most preclinical and clinical studies to date have focused on targeting translation initiation downstream of oncogenic AKT.
Because most of these clinical studies have assessed serum and not cerebrospinal fluid levels of the anti-NR2 antibodies, it is uncertain whether in patients a breach in the blood-brain barrier (a crucial factor in the animal models) has occurred to allow antibody penetration into the brain [ 43].
For most academic clinical studies today, the researcher recruits patients, collects the data, analyzes the data and publishes the results.
The study was of an unusual type for clinical investigations because, unlike most clinical investigations, the participants in this study did not already have a treatable condition.
Most experimental and clinical studies have focussed on the well-studied species C adenovirus, HAdV-C5.
"We don't have proof because those clinical studies are not being carried out!
Most clinical and scientific studies agree that there is a bidirectional relationship between diabetes and depression.
Yet, because clinical studies generally examine efficacy over a period of years, little is known about the time course of the effects of most MS therapeutics [ 2].
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