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Most outstanding mortgages still carry interest rates above 5 percent, despite the availability of lower rates, because it remains difficult to refinance.
However, because it remains difficult to define, a priori, an optimal window size since it would depend on the strength and timing of selection which are expected to be highly variable, we proposed to smooth SNP-specific FST values over each chromosome with a local variable bandwidth kernel estimator (Figures 3, S3, S4 and S5).
Because it remains difficult to differentiate recurrent disease from a second primary cancer, time to development of a new lesion may be an appropriate outcome in this setting.
Finally, despite these successes, new methods that can assess naturally occurring differences in population allele frequencies and LD structure are needed because it remains difficult to know which SNPs are expected or, conversely, not expected to be 'replicable' given inherent genomic architectural differences.
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Because leaf rank is determined subjectively, it remains difficult to be sure precisely what measurable characteristics of the vein network leaf rank describes.
Furthermore, because of the complexity of genetic patterns, it remains difficult to apply genetic preconditions to develop individualized hemorrhage therapy.
Yet it remains difficult to describe Federer's brilliance because his shots, though artistic and graceful, are not showstoppers.
WHO BUYS IN IBIZA It remains difficult to get financing in Spain because of the recession, Ms. Sandig said.
Although FDI has increased in the recent past in Kenya, it remains difficult to quantify the exact magnitude of FDI basically because of the non-reporting problem.
It remains difficult to predict their future".
However it remains difficult to assess objectively.
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