Cholesterol is kept high in the plasma membrane (PM) because it is essential for its barrier function, while low levels are found in the endoplasmic reticulum (ER) where cholesterol mediates feedback control of its own synthesis by sterol-sensor proteins.
Because it is essential to any democracy, its demise will mean, simply, its end as well.
In Lucky Us, nearly every character practises deceit because it is essential for survival.
The pursuit of liberty is worth it because it is essential for the health of society.
Both of these proposals demand wide support, because it is essential that our city provide our seniors affordable housing options.
Should mail be a guaranteed government service — like primary education — because it is essential to our well-being?
For most of us, it is a monopoly service run by a distant bureaucracy that has to be endured because it is essential.
"But I repeat what I said then because it is essential that we learn the lessons of this crisis, so we don't doom ourselves to repeat it.
And in Eurasia, Spykman went on, the maritime rimland is pivotal, because it is essential to the supercontinent's contact with the outside world.
That is because it is essential that the friends, relatives and neighbors of would-be terrorists already living in western countries alert the authorities to dangers in their own communities.
Labor must fight for free education, not because it is something nice to have, but because it is essential to have if we want to live in a knowledge economy with high wages into the future.
