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Because induction of the Venus marker is dependent on hORF expression, addition of doxycycline for 24 hours generated sufficient fluorescence to sort those cells with stable lentivirus integration (Additional file 5).
Because induction of the genes or shRNAs into the breast cancer stem cells are possible by using the lentivirus and the growth of the human breast cancer cells in the mouse xenograft models takes up to three months, we think that it will take three to four months to replicate this experiment.
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In contrast, gradually escalating ER stress by the accumulation of unglycosylated proteins upon treatment with tunicamycin, attenuates translation less dramatically because induction of PPP1R15A limits the degree of eIF2α phosphorylation (Novoa et al., 2001).
Because induction of apoptosis is one of the main mechanisms of anticancer drugs use to stimulate cell death, NEK2A-induced antiapoptosis may explain the high cancer cell drug resistance seen when NEK2A is increased.
Because the induction of the abdominal (enhanced- US, CT, and MRI into thenhanced- USCTne enanded us to detect sMRIler-sinto HCC [ 36], the sensitivity of AFP in the early deteclinical HCC became lescenean 70%.
We hypothesized that diabetic individuals develop cortical or posterior sub-capsular cataracts (PSC) because of the induction of the UPR and production of ROS.
This result suggests that the effect of PGC-1α in promoting survival in the early response to oxidative stress is not because of the induction of the antioxidant defence.
This time range was chosen because, in pulmonate snails, maximal induction of the CdMT gene by Cd2+ is reached only after several days.
This model has been most frequently used and was first discussed by Okayasu et al. in 1990 because of its convenient induction of the disease, lower mortality risk, and defined beginning.
And after heat stress, the cytosolic hsp70 transcription level was about 2.5-fold higher than that of all ER-type homologs, mainly because of the striking induction of the CY-B group, but also due to the significant up-regulation of the CY-A group hsp70s.
However, the interaction of VEGF/VPF with Flk-1/VEGFR2 is thought to be more important for tumor angiogenesis because it is essential for induction of the full spectrum of VEGF/VPF functions [12].
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