Sentence examples for because high doses of from inspiring English sources

He emphasized that megadoses of nutrients were not necessary or desirable because high doses of certain nutrients could have serious negative effects.

This is not to be recommended, because high doses of folic acid are suspected of exacerbating certain cancers.

Non-growth inhibitory doses of α-tocotrienol and its oxazine derivative were selected because high doses of these agents were found to initiate apoptosis and induce cancer cell death, which would confound the interpretation of the results regarding the effects of these agents on tumor cell compensatory response to CoCl2 hypoxia.

This is partly because high doses of stress hormones, particularly noradrenaline, interferes with focus by binding to sites in the prefrontal cortex, stopping it from working effectively.

Additionally, because high doses of metformin can result in reduced lifespan in eat-2 mutants, it appears that when an animal is already in the DR state, further stimulation of DR physiology by metformin leads to diminishing, even harmful, effects, a phenomenon typical of extreme calorie limitation or starvation in C. elegans [34] [36], [39] and mammals [49].

Because high doses of MG induce vomiting, oedema, dizziness and androgen-like side-effects, the ideal effective concentration is difficult to obtain in vivo.

Because higher doses of radiotherapy can lead to increased acute treatment-related morbidity, we recommend using 30 Gy in 10 fractions unless the patient is part of a prospective study evaluating novel biologic or cytotoxic radiosensitizers.

For C. albicans pyelonephritis, both polyenes showed efficacy; because higher doses of the less toxic methyl ester could be used, it sterilized the urinary tract more often than amphotericin B. These studies indicate that in vivo and in vitro experiments may be needed to predict the results of treatment with polyenes.

The 35 mM concentration of EMS was chosen because higher doses of EMS did not result in an increased rate of male lethality in the assay described above.

Because higher doses of methadone are more effective than lower doses in lowering the prevalence of injecting drug use risk behaviour, we considered ≥ 60 mg methadone per day an adequate minimum dosage for opioid replacement therapy and used that dose as cut-off value for our definition of adequate harm reduction [ 11– 13].

The Scientific Committee on Food and the EFSA have set the UL for folic acid at 1,000 µg/d [ 39] because higher doses of folic acid could delay the diagnosis of vitamin B-12 deficiency by masking the anaemia of vitamin B-12 deficiency, which can lead to irreversible neurological damage.