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Because early initiation of immunoglobulin replacement therapy could prevent sequelae associated with infections, early diagnosis is of great importance.
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Were improvements seen in morbidity and mortality simply because more volume was removed because of early initiation of RRT or because patients with more severe disease were not represented in the study?
In patients hospitalized with HF, who are at particularly high risk for re-hospitalization and death, the initiation of β-blockers is often delayed because of concern that early initiation of these agents may exacerbate HF.
However, experts agree that initiation of HAART should not be delayed, because mortality is reduced with early initiation of HAART along with anti-TB treatment [ 24].
It is encountered with increasing frequency because of improvements in prehospital care and early initiation of the Advanced Trauma Life Support.
Even though cell death occurs considerably later (see Figure 1) we selected the 6 hours time point, because we were particularly interested in the early initiation of transcriptional response ultimately leading to cell death.
Our conclusion, in line with literature data, is that very early initiation of the treatment is beneficial because it can down-regulate the immune activation, hence limiting viral replication and spread.
The development of reliable models in which the early initiation of child breastfeeding (BF) is in focus is imperative, because this feeding behaviour has such profound consequences for the mother's and child's health.
An Institute of Medicine committee on under-age drinking has said there is "a strong possibility" that youth exposure to alcohol through movies contributes to early initiation of alcohol use.
A meta-analysis of these data suggests a benefit of early initiation of RRT [8].
Three prospective open studies found no benefit of early initiation of RRT [12 14].
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