Because earlier work has shown differential rodent strain neurodegeneration susceptibility to neurotoxin [ 22], we then investigated whether two common laboratory rat strains, i.e., Sprague Dawley and Wistar, would display a different susceptibility to hα-syn overexpression.
We chose to compare JR1 directly with three previously studied styryl dyes, under identical conditions, because earlier work has shown that a dye's response to an electric field can depend on experimental parameters such as the composition of the lipid bilayer, the laser wavelength, and the time scale of the measurement.
Because earlier work had hinted at a protective role for hemoglobin C as well, a team led by Mario Coluzzi and David Modiano of the University of Rome La Sapienza decided to explore it further.
Subjects from both 4 mg and 8 mg dose cohorts in VRC 004 were included because earlier work had shown no significant differences in the frequency, magnitude or quality of response to primary DNA immunization between dose levels [20].
Our discovery of Reck's central role in Wnt/β-catenin signaling is surprising because earlier work had implicated Reck in tissue remodeling via inhibition of MMP function at the transcriptional level (Takagi et al., 2009), and at the level of protein protein interactions (Takahashi et al., 1998).
Partly because of its own undoubted quality, partly because the earlier work has enjoyed such success in London and New York, this is the piece that was to have reopened the Royal Court Theater, which has been closed for nearly four years for a $40-million 40-million refit
Because our earlier work has found that both MA and MO groups show very significant sensitivity to flicker (9, 10), we did not attempt to recruit separate MA and MO groups.
However, this earlier work has been criticized because explicit phoneme classification is never necessary in linguistic communication, and effects could have emerged at the level of phoneme classification, rather than perception per se (Hickok 2009; McGettigan et al. 2010).
We started by first examining a potential role of PI3K as a primary target (Fig. 3), because our earlier work had implicated this activity (Xu et al., 2007).
Earlier work had provided some clues.
At that time, the fear was largely theoretical because Ibsen's early work had not travelled much further than Sweden.
