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Results may not generalize to other cities, states, or regions in the United States or abroad because data were gathered from one mixed-urban school district.
Finally, because data were gathered as part of a cluster RCT, 22 in order to enable completion of all instruments during a 55 min class, a shortened version of an instrument to assess sun-related knowledge, behaviour and tanning attitudes 19 was used which meant that replication of analysis conducted elsewhere using the full instrument could not be conducted.
Furthermore, information bias is unlikely because data were gathered prospectively and because the use of digital ECG recordings all measured using the automatic MEANS system likely reduced intra- and interobserver variability in the assessment of the QTc, QT and RR intervals.
In addition, because data were gathered from electronic medical charts, without data from face-to-face interviews, some information on risk factors previously identified, such as symptomatic characteristics (i.e., self-devaluation, hopelessness, and insomnia) and poor adherence to medications [ 22] have not been available.
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Clinicians and medical assistants are responsible for complete and accurate data collection, because data is gathered during routine patient care.
According to the Dutch legislation informed consent was not required because data is gathered after patients' death and the study involves no more than minimal risk to the participants.
Because the data were gathered at one time point, only step A and C models are applicable.
Another limitation was posed by our cross-sectional study design, which did not allow us to determine causality because all data were gathered at the same time.
However, because our data were gathered before the diagnosis of ovarian cancer, misclassification would be expected to be nondifferential between cases and noncases and would tend to attenuate any true relationship.
These behaviors subsequently were condensed into broader categories to account for possible ambiguity in interpreting behavioral transitions because the data were gathered via scan sampling as opposed to continuous observation (Table 1).
There should also be some consideration of gathering pharmaco-kinetic data after dietary administration because the existing data were gathered after gavage or intravenous administration.
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CEO of Professional Science Editing for Scientists @ prosciediting.com