Sentence examples for because constitutive expression of from inspiring English sources

Likely because constitutive expression of rtTA is toxic and also leads to higher background expression of the regulated gene.

Because constitutive expression of Esrrb blocks differentiation, transgene excision (Chambers et al., 2003; Niwa et al., 2009) was necessary to determine whether ESCs maintained by Esrrb retain pluripotency.

The alternative pathway of NF-κB activation may be implicated in TLO generation, because constitutive expression of LTβ in target tissues has been shown to cause TLO formation [ 67].

Initial attempts to generate 3T3-L1 preadipocell celinesnestablyly over-expressing Egr1 using a retroviral vector were unsuccessful (data not shown), possibly because constitutive expression of Egr1 at high levels is inhibitory to proliferation (21).

Because constitutive expression of RACK1B or RACK1C could efficiently complement rack1a mutant's developmental defects, these results implied that RACK1B and RACK1C are likely in principle functionally equivalent to RACK1A, and that the unequal genetic redundancy of RACK1 genes is likely due to the difference in their expression patterns or expression levels.

However, it is also clear that Tcl1 is not the only primary Oct3/4 target gene that controls proliferation in ES cells, because the constitutive expression of Tcl1 cannot prevent the reduction of proliferation by the repression of Oct3/4 (Figure 6E).

In summary, the results presented in this manuscript are important because they demonstrate constitutive expression of IL-33 in the nucleus of endothelial cells and epithelial cells in normal human tissues.

Because of the constitutive expression of CD45RB in normal microglia, quantitative analysis did not reveal that CD45RB counts were significantly increased in HIVE.

An increase in TPP biosynthesis can be anticipated because of the high-level constitutive expression of the exogenous PDC [ 31].

Fluorescence present in the non-irradiated control is because of the low-level constitutive expression of the RecA promoter (Nuyts et al, 2001a).

Our results are consistent with these data because they clearly show that constitutive expression of GEF16 mRNA induces the formation of multiple transformed foci in NIH3T3 cells after 12 days of growth in the presence of G418.