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The observed pattern of expression of the hair follicle cytokeratins is consistent with such a model, in that the aberrant markers (mIRSa.2, mIRSa.3.1) are generally expressed in localized foci of cells, as would be expected for a clone of tumor cells descended from a single progenitor cell that became specified for a particular epithelial compartment stochastically.
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How exactly neural crest cells become specified has been a bone of contention for some time (Schlosser, 2008, Weston and Thiery, 2015, Simões-Costa and Bronner, 2015).
Then, one becomes specified as an axon, while the others become processes specialized for receiving signals, called dendrites.
However, how the AVE becomes specified and the dynamics of its formation currently remain unclear.
Among cardiac mesoderm, progenitors for the two heart fields diverge soon after the initiation of gastrulation and rapidly become specified into discrete populations of committed precursors.
After the time specified for states to sign the treaty has passed, states may become parties to the treaty through a process known as accession.
No date was specified for its introduction.
Office specified for data analysis.
But no role is specified for the Council.
(No state dollars are specified for his teacher-bonus proposal).
We believe that our approach, though rudimentary, is biologically more relevant and that in the near future the link between the octoploid sub-genomes and their diploid and tetraploid ancestors will become better specified, as has occurred for bread wheat [ 23].
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