The humerus was the most frequent site of NU in women (3.54/100 000 population) and this became a greater problem with increasing age, representing the increasing number of osteopaenia-related proximal humerus fractures in the elderly.
The introduction of Research and Development units in NHS Trusts may have created ownership and a business model for research, at the expense of some uniformity and cooperation between individual organisations, whose varying interpretation of the regulations led to bureaucratic delays, a process which became a greater problem after the implementation of the EU clinical trials directive in 2001.
Groundwater contamination has become a great problem due to rapid growth rate of population, industrialization and urbanization in the metropolitan city all over the world.
Obesity has become a great problem all over the world.
This can become a great problem, when API source, site of manufacturing, or manufacturing equipment is changed.
Most teachers in all four contexts expected cheating to become a greater problem with increased use of e-assessment.
"Based on the changes in the climate and changes in the weather, predicting the nutrient enrichment of systems is going to continue to become a greater problem," said Euan Reavie, a senior research associate studying algae at the University of Minnesota Duluth.
Diseases of wild salmon likely to become a greater problem with warmer temperatures include those caused by the myxosporidian parasite Ceratomyxa shasta, the bacterium Flexibacter columnaris, and by various Aeromonas and Listonella species (McCullough 1999).
Having a grip on exactly what the problem was became a great help to my family.
Russia became a great power, without whose concurrence no important European problem could thenceforth be settled.
