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The expression of each target in the samples bearing driver alterations of the TF and unaltered samples were then compared using a Mann–Whitney test.
S100A2, which also appears upregulated in samples bearing driver alterations of TP53 (Fig. 3c) has been related to tumor promoting processes, such as the epithelial-mesenchymal transition.
Finally, I compared the expression level of the target of each driver TF in the tumor samples bearing driver alterations with that of the samples where it was unaltered.
To that end, I first repeated the search for significant targets detailed in the previous section comparing this time the expression of targets of the TF in samples bearing driver alterations of the partner and samples where neither the partner nor the TF bore driver alterations.
I then repeated the process of identifying significantly misregulated genes – within the set of targets of the TF – between the group of tumor samples bearing driver alterations of the partner and the tumors where neither the partner nor the driver TF were altered.
For bearings that can be pushed out, take a socket or bearing driver of roughly the same diameter as the exposed outer ring of the bearing.
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In addition, note that the detection of differentially expressed targets of a TF is done previously to the detection of its partners and thus the set of samples bearing no driver mutations may actually include samples where a connected driver bears a mutation that result in the misregulation of the TF targets.
Jack Brabham's 1966 Drivers' Championship remains the only such achievement using a car bearing the driver's own name.
The BT19, which Brabham referred to as his "Old Nail", was the first car bearing its driver's name to win a World Championship race.
By definition, information-bearing drivers are not necessarily the primary cause of spontaneous activity in their thalamic targets (Sherman and Guillery 2006).
At the Gare du Nord, there is a driver, bearing your name.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com