Sentence examples for bear defects from inspiring English sources

Breast tumors arising from hereditary BRCA mutation carriers are mostly triple-negative and share a striking resemblance to sporadic basal-like and triple-negative breast cancers suggesting that TNBC might bear defects in DNA repair thereby endowing a degree of "BRCAness" on these cancers [ 9].

XP patients bear molecular defects either in nucleotide excision repair (NER) or in translesion synthesis (TLS).

Although the miR-dKO sperm completely lack all five miRNAs, the caveats of using miR-dKO sperm for ICSI lies in that these sperm are mostly deformed due to disrupted spermiogenesis, and thus, may bear structural defects and compromised integrity of the paternal genome in addition to the lack of five sperm-borne RNAs.

The generation and characterisation of the mutants in the Synechocystis sp. PCC 6803 photorespiratory pathway, i.e., ΔglcD1, which bears a defect in the glycolate dehydrogenase-coding gene sll0404, and ΔgcvT, which bears a defect in the gene sll0171 that encodes the T-protein subunit of the glycine decarboxylase complex, have been described elsewhere [13], [28].

Sub-Tg (glass transition temperature) thermal annealing was used to stabilize large bore size defect-free Matrimid® hollow fibers by suppressing the HAc-induced plasticization.

One possibility is that the pollen bears a defect that leads to pollen sterility and inability to fertilize the embryos.

The morphological changes and marked reduction of thymocyte numbers observed in our DG/Lck-cre mice are reminiscent of the phenotype in the thymus of (dy/dy) and (dy3k/dy3k) mice that bear a genetic defect in the laminin α2 chain, a major high affinity ligand of α-DG.

43 LS mutation carriers bear an innate defect of their MMR machinery for which no cure is in sight.

To date, most oncogene-bearing transgenic mice and tumour suppressor gene knockouts have had a whole-body phenotype, in which all tissues and cells bear the same defect.

Mitochondria are central to the regulation of cellular energy homeostasis and redox balance and have been shown to bear the causal defect in some cytoplasmic male sterility (CMS) species.

TEIPP-specific CTLs and their cognate peptide-epitopes provide a new strategy to counteract immune evasion by APM defects and bear potential to targeting escape variants observed in a wide range of cancers.