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The generation and characterisation of the mutants in the Synechocystis sp. PCC 6803 photorespiratory pathway, i.e., ΔglcD1, which bears a defect in the glycolate dehydrogenase-coding gene sll0404, and ΔgcvT, which bears a defect in the gene sll0171 that encodes the T-protein subunit of the glycine decarboxylase complex, have been described elsewhere [13], [28].
One possibility is that the pollen bears a defect that leads to pollen sterility and inability to fertilize the embryos.
The morphological changes and marked reduction of thymocyte numbers observed in our DG/Lck-cre mice are reminiscent of the phenotype in the thymus of (dy/dy) and (dy3k/dy3k) mice that bear a genetic defect in the laminin α2 chain, a major high affinity ligand of α-DG.
43 LS mutation carriers bear an innate defect of their MMR machinery for which no cure is in sight.
The NZB/W mouse, a model for SLE, bears a genetic defect in the TNFα gene that leads to reduced levels of TNFα [ 20].
A nipbl-deficiency model in zebrafish shows altered expression of genes involved in endodermal differentiation along with a spectrum of heart, gut, and visceral organ defects that bear a striking similarity to those observed in CdLS patients.
NOD 2, a defect present in approximately 50% of Crohn's disease patients, bears no relationship to non-response.
This is not a defect.
But, it's not a defect.
That's a defect in some respects.
"It is a defect in my nature".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com