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Our results show that HT29 cells can be well sensitized toward MTX by simultaneous treatment with siCAV1 and pBATEM2-CDH.
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As is well known, scenarios sensitize and enlighten their users to think more broadly about futures.
Given that thiazolides are well tolerated, and sensitize tumor cells to chemotherapeutic drugs, the combined use of thiazolides with other anti-cancer drugs may also allow to administer lower drug doses with similar anti-tumor efficacy but reduced side effects on tissue cells.
In addition to their insulin sensitizing function, TZDs are well known to induce thermogenic gene expression in both white and brown adipocytes (Sell et al. 2004; Rong et al. 2007; Petrovic et al. 2010; Qiang et al. 2012).
Increased leptin, the satiety hormone, and decreased adiponectin, the insulin sensitizing adipocytokine, have been well established among those with increased body fat [11] [12].
It is well known that the waiting time for highly sensitized (HS) patients is much longer than for who are not sensitized and a longer time on dialysis has demonstrated to be a negative impact on graft survival [ 2].
It is well documented that cells lacking HR function are greatly sensitized to a panel of DNA damaging agents, including MMC [26].
Cyclin D1 (CCND1) is well known as a DNA repair gene and might sensitize human cancers to radiation by limiting DNA repair [ 15].
At baseline, the patients who were sensitized to more than one allergen (polysensitized) were well matched across the treatment groups.
The 'two for one' cross-relaxation process labelled C1 that feeds the 3F4 state is well known for Tm3+ and has been used in YAG [7] and YLF [8] host crystals to sensitize 2-μm sources for diode pumping.
It is well known that MCF7 cell is relatively insensitive to many cancer chemotherapy drugs and reconstitution of caspase-3 sensitizes MCF7 cells to drug-induced apoptosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com