Sentence examples for be very difficult since from inspiring English sources

Development of a drug blocking the activation of (P RR by renin proved to be very difficult, since structure function studies and crystallographic data are lacking.

Therefore, detecting endothelial cells undergoing apoptosis after multiple rounds of treatment may be very difficult, since the bulk of the potentially ZD6126-sensitive endothelial cells throughout the tumour would be affected at the earliest times of the treatment regimen.

Matching texture can be very difficult since it is usually machine blown.

Creating a Fraternity on your own can be very difficult, since you will only be helped when you are starting a chapter of an already existing Fraternity.

"It's been very difficult since then and we're barely making it," she said.

"Things here in Freetown have been very difficult since Ebola struck.

There have been great periods – for instance, during and after the second world war when cinema found a great patriotic purpose and had a major role in society that was recognised – but it has been very difficult since then to make a career in British cinema.

Manufacturing of synthetic composites consumes huge energy and their disposal at the end of the life cycle is very difficult since there is virtually no recycling option.

Assessing software quality at the early stages of the design and development process is very difficult since most of the software quality characteristics are not directly measurable.

Evaluating (5) is very difficult since there is no consensus on whether kinds have essences (Quine would say 'no') and there is no consensus among those who assert the existence of essences as to what they are.

At a stop (unless you're exceptionally short), seeing the light change is very difficult, since the rake of the windshield is steep and the opening is quite small.