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Some of the derivatives were found to be very active against the cultured (epimastigote) form of the parasite, being 1.5 1.7-fold 1.5 1.7-foldthan the reference comorend, Nifurtimox.
Some of the derivatives were found to be very active against the epimastigote form of the parasite, being near to 3.0-fold more active than the reference compound, nifurtimox.
In an antimicrobial agar diffusion test, the crude extract of S. ilicifolium was found to be very active against the Gram-negative bacteria Shigella boydii and Klebsiella oxytoca, the Gram-positive bacteria Streptococcus pneumoniae and Staphylococcus aureus, and the yeasts Candida membranaefaciens, Trichosporon mucoides, and Cryptococcus neoformans (Table 3).
The basis for selecting EXEG 1706 was a newly designed family of compounds that were found to be very active against TB and MRSA using disc assays and Minimal Inhibitory Concentration (MIC) assays.
PS, JCP1 and JCP2 were found to be very active against MCF-7 cells by inducing anoikis and therefore possessing vast potential as medicinal drugs especially in estrogen receptor positive breast cancer treatment.
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Ceftazidime is a third-generation cephalosporin (molecular size 636.6 Da) with a broad spectrum of antibacterial activity (it is very active against Pseudomonas aeruginosa) and is commonly used in intensive care units.
Tests at one of the consortium's laboratories showed that the compound was very active against the cancer.
Interestingly, 7B was very active against MDA-MB468 (IC50 = 0.12 μM), but not against other cell lines examined.
ACV dipeptide esters were very active against herpetic viruses, independently of the rate at which they liberate the parent drug.
The results showed that CHXTP salt is very active against Streptococcus mutans, with no interference on taste perception and a low tendency to stain; however, chlorhexidine digluconate shows a better retention in saliva.
He found that the broth in which it was cultivated was very active against certain types of bacteria, and that it owed this property to a substance secreted by the mould; and he suggested that it might be used as an antiseptic in wounds.
More suggestions(16)
be very inhibitory against
be very difficult against
be very stable against
be very offensive against
be very potent against
be very susceptible against
be very outspoken against
be very competitive against
be very tough against
be very obvious against
be very resistant against
be very firm against
be very useful against
be very destructive against
be very clinical against
be very robust against
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com