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In parallel, more detailed characterization of the functional effects of potential activating mutations in MTOR and RHEB (Grabiner et al., 2014) would be valuable in refining entry criteria for rapalog trials.
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CTD is valuable in refining biomarker candidates and addressing questions about whether a gene is responsive to a specific chemical or representative of a more general stress response.
This approach reflects regulator views that DNT data are valuable in refining permissible exposure levels and that the absence of these data can increase the uncertainty about the toxicity of the chemicals (U.S. EPA 2002a, 2002b).
We suggest that the systematic collection of IR data from ISTs obtained with IVV, in addition to data collected by other methods such as Y2H, will be valuable for refining our understanding of protein interactions.
It was valuable in and of itself.
Transparency is valuable in programs so secret.
They are valuable in any industry".
Animal models are valuable in transfusion research.
That's valuable in itself.
Therefore, CTC detection and characterization may be valuable tools for refining prognosis, and CTCs can be used in a real-time tumor biopsy for designing individually tailored therapy against CRC.
Such partnerships can be particularly valuable in refining or formalising theories before, during or even after the work is done.
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