Sentence examples for be validated in large from inspiring English sources
These data, which need to be validated in large prospective clinical trials, might represent a valid platform for oncologists in selecting patients for cetuximab-based therapy, with evident clinical and economical consequences.
Treatment with immune checkpoint blockade (CPB) therapies often leads to prolonged responses in patients with metastatic melanoma, but the common mechanisms of primary and acquired resistance to these agents remain incompletely characterized and have yet to be validated in large cohorts.
As new developments in diagnosis and promising therapies tested in animals and humans will emerge, they will need to be validated in large clinical trials to confirm the safety and efficacy of their use in septic patients.
In addition, predictors of prolonged ventilatory support in trauma need to be validated in large studies.
This concept has to be validated in large prospective clinical studies.
These techniques show promise but remain to be validated in large population-based or clinical study samples.
All of the biomarkers identified so far must be validated in larger independent clinical cohorts.
All of the cancer studies to date are preclinical studies in mice and may need to be validated in larger animal studies such as dogs or sheep before moving into human clinical trials.
These results should be validated in larger studies.
Findings should be validated in larger, controlled studies in animals and humans using a range of targets and classes of drugs.
