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Appropriate biochemical and cell assays provide quantitative measurements, and for biomedical impacts, any inhibitor's activity should be validated in human cells.
Ultimately, the correlation of data generated in experimental animal models must be validated in human studies, if the microRNA in question are to be proposed as a pathogenic mediator of clinical BPD.
These findings have to be validated in human trials.
These changes remain to be validated in human brain tissues.
These biomarkers have to be validated in human trials.
Because many studies involve animal experiments, their results should also be validated in human samples.
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Furthermore, the miR-511-TNFR1 miR-511-TNFR1 miR-511-TNFR1d in humaxis
The use of agents that block the action of polynuclear cells or cytokines has been promising in experimental meningitis, but has yet to be validated in humans.
The CSC form of the material has performed well in an animal model [ 37] but the results and effectiveness need to be validated in humans.
The second major drawback of non-human model systems is inherent even in the genetically equivalent mouse models: modifiers identified in these systems must still be validated in humans, as they may reflect biology peculiar to the model organism used.
Although these findings remain to be validated in humans, they could provide an explanation for the differences in susceptibility and age-at-onset of aging-associated neurodegeneration, which may be due to natural genetic variation and differences in exposure to environmental factors that influence disease-specific modifying processes.
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be verified in human
be demonstrated in human
be investigated in human
be replicated in human
be identified in human
be rooted in human
be caused in human
be used in human
be detected in human
be tested in human
be involved in human
be applied in human
be determined in human
be related in human
be understood in human
be validated in clinical
be accelerated in human
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