However, despite its limitations, we strongly believe that this rational strategy will help us to identify candidate biomarkers and proteins that will eventually be validated further as a potential drug targets for prostate cancer.
The utility of this method for AIG will be validated further.
Scripts, topics, and timeframes that were initially devised by content experts were validated further and revised for direct use or adaptation by clinicians in the conduct of focus group sessions for parents/guardians, siblings, and affected children.
Further studies are required to assess the in vivo anti proliferative potential of CA. CA and any other analogs derived from it may be explored and validated further for its usefulness as anti cancer agents for retinoblastoma and other cancers.
However, there are no overlapping genes between our results and the gene signature identified by gene expression profiling of CD44+CD24- breast cancer stem-like cells [ 46]; therefore, our findings should be validated in further studies, for example, analysis of stem cell marker expression.
However, these hypotheses need to be validated by further experiments with different inhibitors for the same targets or with alternative methods, e.g. using siRNA.
Since the microarray results could not be validated for the 7dpi-0dpi dataset, further network analyses were only performed on the 4dpi-0dpi dataset.
However, it is recommended that the stable expression of candidate reference genes identified by PlantRGS should further be validated experimentally before using for normalization.
This indicates that good agreement is achieved and the finite-element model is validated for further analyses.
The screening and preclinical evaluation of small-molecule drugs targeting histone modifications need to be validated in small animals before proceeding further for toxicological studies, and then on to clinical trials.
The models were validated and further used for docking analysis with sulphate inhibitor.
