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Some of these abnormally activated protein kinases will be validated as causal of disease, and therefore "targets".
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In many of these studies, genes at the identified loci were validated as causal using engineered mouse models and a number of the loci or genes corresponded to human GWAS results.
All primers were validated as described [55].
The possibility of true causal effects, however, needs to be validated by prospective observational and randomized trials.
Anything can be validated.
It can be intuitively validated as well.
The strategy was validated this winter as mild weather and post-Sept.
A middle-aged stud is as panicked as he is validated.
Such a causal relationship has also been validated in other contexts, such as consumers' acceptance of mobile payment services [ 46], users' employment of mobile map services [ 47] and players' acceptance of mobile social network games [ 48].
This causal model has been validated in acute [ 14, 15] and mental health hospital [ 11] settings.
Episkin was validated this year by European regulators as a test tool that could fully replace animals.
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