Sentence examples for be valid targets of from inspiring English sources

Despite the disappointing overlap, some of the genes identified in these two studies are still likely to be valid targets of ER signaling.

Our findings demonstrate that cancer associated fibroblasts promote tumor growth and metastasis through their role as key modulators of immune polarization in the tumor microenvironment and are valid targets for therapy of metastatic breast cancer.

In our view, there is sufficient evidence suggesting that lipid rafts are valid targets for the development of new pharmaceuticals capable of modifying their function in autoimmunity.

There is also evidence that NRPs are valid targets for therapeutic inhibition of angiogenesis and cancer (Caunt et al, 2008; Goel et al, 2012a; Gray et al, 2008; Pan et al, 2007).

Thus, all of these clusters consist exclusively of irrelevant genes and are valid targets for a chassis construction.

Many of these predictions may be valid targets.

CDKs are valid targets as they function as essential regulators of cell growth and differentiation.

"Most of the people who died were valid targets and those who were caught up in the attacks will be accepted by God," he said.

The efficacy of the present compounds as inhibitors of ERK-substrate interactions and their activity in a xenograft mouse model [ 41] further indicate that protein-protein interactions are valid therapeutic targets of LMW compounds.

Since thiazole antibiotics suppress the expression and the activity of FoxM1 and at the same time FoxM1 overexpression protects cancer cells from Siomycin A and thiostrepton toxicity, FoxM1 may be a valid target of thiazole antibiotic-induced apoptosis.

Consistent with this direct evidence, we further obtained additional data in support of HDAC4 being a valid target of miR-10b, and we found significantly down-regulated expression of HDAC4 in high miR-10b expressing MCF7TR cells (Fig.  4d).