The process of creating, controlling, using, and distributing frames and narratives, including negotiations over which actors, knowledge, and expertise are valid and relevant, is often hotly contested and debated.
As the pain catastrophizing scale is valid and relevant for both patients and healthy controls (referring to any pain experienced rather than to pelvic pain specifically), acceptable to patients/controls, and comprises of only 13 questions, we consider this to be an important covariate in interpreting other pain-related information and thus have included it in the EPHect EPQ.
All in all, although more detailed and refined analysis are certainly possible, we consider our results to be valid and clinically relevant.
These conclusions are valid and particularly relevant, not only because of the large sample size and long duration of follow-up, but also due to the fact that we analyzed the clinical, serological and long-term outcomes in terms of relapses.
Recently, the FDA ruled that both TTP and PFS are valid and clinically relevant TDEs that can be used in the accelerated approval process for MM agents [ 17].
tuberculosis H37Rv PPIs predicted by our stringent homology-based approach are valid and very relevant to the infection process of M. tuberculosis H37Rv.
What is the burden of proof that such models are valid and predictive of clinically relevant outcomes?
They can hardly know where to start when deciding whether the relevant literature is valid and of the highest quality.
When new end points or metrics can be shown to be valid, relevant, and reliable for assessing hazard and risk, they can be and are incorporated into new and revised OECD test guidelines.
Easy contribution encourages users' participation and improves the sensing task but may result in large amounts of data, which may not be valid or relevant.
