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Based on the published literature, the authors made recommendations on how the focal principles, such as test-driven development or requirements management, should be utilized to evade the issues.
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A turbulence operator is utilized to evade local optima, for further improving the search ability.
In conclusion, these emerging strategies can be used to enhance tissue tropism and can also be utilized to produce AAV that are able to evade neutralizing antibodies, at least partially.
PCR amplifications were utilized to close gaps.
Biofilm formation is an efficient mechanism that bacteria utilize to evade recognition and elimination by the host immune system.
One mechanism that H. capsulatum purportedly utilizes to evade oxidative stress is the production of catalases [5].
On the one hand, snoRNA can act as mediators of host antiviral response; on the other hand, the activity of regulatory RNAs can be utilized by viruses to evade innate immunity and complete their life cycle [ 80].
Many viruses, like their hosts, encode miRNAs, which can be utilized by viruses to inhibit host cell apoptosis, evade the host immune system, regulate the viral life cycle, and control viral gene expression [3].
PPSA complexation enabled Ad to evade both innate and adaptive immune responses against Ad, implying that Ad/PPSA nanocomplex can be utilized for systemic multidose treatment.
These MAbs will be utilized for structural mapping of antigenic footprints on their respective capsids to inform development of the next generation of rAAV vectors capable of evading antibody neutralization while retaining parental tropism.
These results clearly demonstrate that PPSA complexation can evade pre-existing neutralizing antibodies, and further imply that Ad/PPSA nanocomplex can be utilized for systemic multidose treatment.
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