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With adequate animal datasets, dose response modeling can be utilized; however, the risk assessor often resorts to a default method known as the no observed adverse effect level (NOAEL) approach, put in place to deal with the problem of having limited dose response data.

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To address their issue, usually a high level of chemical treatment is utilized; however, the addition of such level of chemicals itself creates another issue such as high concentrated sludge.

Ideally, human primary hepatocytes would be utilized; however, these come with limitations, including availability, culturing times, the effect of isolation on function, terminal differentiation, and lack of robust cryopreservation techniques.

Any scene change detection algorithm can be utilized, however.

Measures may be utilized however unstructured/semi-structured clinical interviews predominate.

When bootstrap is utilized, however, a more powerful test than the bootstrapped D-W test can be designed.

For PN recipients, the actual number of hospital days before and after PN were utilized; however, for non-PN recipients equivalent timeframes were created based on the average number of days prior to and during actual PN administration.

Most commonly, Pt counter electrodes are utilized; however, despite their excellent properties, they suffer from several limitations, e.g., difficulty in large-scale production and high economic cost.

Corticosteroids are widely utilized; however, the toxicity (eg, increased risk of fungal infections) associated with the use of these agents is often large.

Nonmyeloablative preparatory regimens followed by HLA-matched related or unrelated bone marrow have also been utilized successfully; however, the data using these approaches are limited.

However, this approach cannot be utilized in the absence of experimental modulation of brain activity such as during resting state.

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