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The routine use of molecular methods could be useful to screen candidate babies for etiologic therapy.
85 Neuropathological studies have shown that white matter hyperintensities usually represent pathological small vessel disease, 3 5 therefore white matter lesions may be useful to screen treatments before evaluation in much larger clinical studies, using stroke and dementia as clinical end points.
For this reason, magnetic resonance imaging (MRI) can be useful to screen for concomitant multiple ligament injury, meniscal lesions, or combined cartilage defects.
First, however, many more women with early stage ovarian cancer must be tested to determine whether it would be useful to screen healthy women and those at high risk for developing ovarian cancer.
The quantitative, high-content assay will be useful to screen for less-toxic retinoids or combinations of agents that promote myoblast differentiation in the presence of TGF-β1.
Mold allergy tests may be useful to screen for children and adults who are at greatly increased risk of developing severe or fatal asthma.
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The cut-off 10/11 for major and minor combined depression is useful to screen for a posterior psychiatric evaluation in Spanish sample.
Non-mammalian systems like Drosophila and cellular models are useful to screen potential genetic modifiers of mutant huntingtin aggregates.
Developing guidelines and training of health workers in TB clinics is useful to screen and treat depression and anxiety among TB patients.
These transgenic mice develop progressive motor neuron loss and neurological deficits and, although not perfectly predictive of human ALS, are useful to screen potential drugs for clinical trial.
Similarly, microarray technology, which focuses on detection of nucleic acid fragments corresponding to different pathogens, is useful to screen a sample for the many pathogens on a wide differential diagnosis for infectious symptoms in a given region [ 10].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com