Sentence examples for be useful modulators of from inspiring English sources
Bivalent ligands, in which two identical binding groups are linked by a spacer unit, can have exceptionally high binding affinity, and can, consequently, be useful modulators of biological function.
New generation LXR agonists with less lipogenic profiles are currently being developed, and we postulate that such agonists may be useful modulators of myocyte metabolism in the prevention of pathological cardiac remodeling and heart failure.
These data confirm MDR1 and MRP expression as contributory factors in chemoresistance in neuroblastoma and indicate that VX-710 may be a useful modulator of both mechanisms and worthy of clinical evaluation in this tumour.
The 3D system developed will be useful for systematic investigation of the modulators of in vitro matrix mineralisation by osteoblasts in mechanobiology and tissue engineering studies.
The cellular mechanisms of human poly-glutamine (polyQ -related disease are conserved in invertebrates, and fly models of polyQ -related have proven to be useful for idiseaseing are conservedininvertebratess of neurodegenerandon.
These results suggest that InCell SMART-i will be useful for identifying targets of small-molecule modulators from phenotypic screening for development of molecular probes by biochemical approaches.[ 1, 12] In summary, we have developed a novel and effective readout for specific molecular interactions inside living cells by monitoring the induced assembly of nanoclusters.
The final QSAR models as well as the information gathered from 3D contour maps should be useful for the design of novel ERα modulators having improved affinity and potency.
These similarities in otherwise unrelated proteins can be useful in the design of protein function modulators.
Tumor-targeted ATF2 modulators may be useful as sensitizers in the treatment of ATF2-overexpressing tumors [ 53].
Modulators of hAS3MT activity may be useful for the prevention or treatment of arsenic-related diseases.
Therefore, strategies that identify and analyze new modulators of autophagy may be useful.
