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These copolymers may be useful in protein delivery systems.
The prediction of catalytic residues in newly solved protein structures is highly desirable in structural proteomics and should help to further our understanding of catalytic mechanisms, which will be useful in protein engineering and in functional annotation.
This is the most extensive in silico protein subcellular localization identification to date for Leptospira interrogans serovar Lai genome that may be useful in protein annotation, discovery of novel genes and understanding the biology of Leptospira.
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Finally, the flexibility of our cassette-based strategy opens new opportunities for the design of tandem affinity purification (TAP) tags [ 8], which were useful in protein complex purification in the yeast proteome [ 9].
This expression platform features high throughput cloning, high flexibility for different constructs, and high efficiency for membrane protein overexpression, and is expected to be useful in membrane protein structural and functional studies.
The cytotoxic variants of HPR will be useful in designing protein therapeutics with low immunogenicity.
A clear definition of interologs and their applicability to estimate the reliability of HTP experiments [14], [15] have been found to be useful in expanding protein interaction networks [12], [16] [18].
Thus, although the average accuracy of the ANGLOR prediction is still low, the portion of the accurately predicted dihedral angles may be useful in assisting protein fold recognition and ab initio 3D structure modeling.
This data would be useful in researching protein classification and evolution rates.
These distant relationships would be useful in annotating protein functions and designing experiments.
Although the method is typically used for screening a library of potential inhibitors (Kitchen et al., 2004), it can also be useful in computational protein design (Kraemer-Pecore et al., 2001).
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