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The results are consistent with production of a high-quality library that will be useful for functional genomics studies using other assays.
The ability to suppress multiple genes simultaneously using electroporated siRNA indicated that this approach might be useful for functional modulation of the RB and p53 pathways.
The analysis of the corresponding protein interaction networks can be useful for functional annotation of previously uncharacterized genes as well as for revealing additional functionality of known genes.
This approach will be useful for functional study of the importance of niche factors in normal and malignant human hematopoiesis.
Probes modified with strings of fluorescent tags allow for high level multiplexing (>16,000) when detected by optical microscopy; this platform may be useful for functional genomics studies [14].
Quantitative expression analysis under different conditions will be useful for functional predictions.
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Therefore, as both the G130V and I154F mutant clones display a stable and spontaneous biochemical phenotype and are able to proliferate in classical culture conditions, these new cellular models will be useful for functional-based large-scale drug screening.
Nucleosomes reconstituted from bacterially expressed histones are useful for functional and structural analyses of histone variants, histone mutants, and histone post-translational modifications.
While this method is useful for functional alignment and decoding, it may also provide a basis for brain-to-brain communication using the converted pattern for designing brain stimulation.
These data indicated that reversible impairment of ku80 in A. aculeatus is useful for functional genomics in cases where genetic segregation is not feasible.
This information is useful for functional annotation and is often essential to enable in vitro protein expression and future biochemical characterization.
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