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We used three approaches to study class-characteristic gene regulation that may be useful for discrimination of compound classes.
By visual inspection of the data, it was hypothesised that different features in the radar data might be identified that could be useful for discrimination purposes.
Recently, quantification of P. jirovecii DNA by real-time PCR targeting the heat shock protein 70 gene was reported to be useful for discrimination between colonization and infection with this organism [ 34].
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Within such promoter CpG islands, there were many CpG sites where DNA methylation levels were useful for discrimination of CIMP-positive ccRCCs in the learning cohort from CIMP-negative ccRCCs (Additional file 8: Table S6).
In this method, voxelwise correlations between RAVENS maps and group membership are used to identify voxels that are candidates to be useful for intergroup discrimination.
In addition to the problem of decomposition being interesting and important in its own right [2], decomposition has also proven to be useful for texture discrimination [3], image denoising [4], image inpainting [5] and image registration [6].
The proposed method, by greatly enhancing the sensitivity of microarray studies, allows the identification of important aspects of genetic regulation networks and might be useful for the discrimination of the different players involved in regulation circuits.
Sequences of PRAC and HyPRE were aligned and residues that may be useful for their discrimination were identified (Figure 5).
Fibromodulin catabolism on the other hand was more uniquely associated with articular cartilage and could be useful for tissue discrimination.
In Arachis, SSR markers have been recently developed and proved to be useful for accession discrimination and assessment of genetic variation [ 19, 22, 23].
Thus, this PCR system was thought to be useful for the discrimination of MTC species, especially for the screening of naturally pyrazinamide-resistant species with only one PCR reaction per sample.
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