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MPIO have been shown to be useful for cellular MRI, enabling in vivo detection of single cells [35] and cell tracking [8] using only a small number of MPIO.
Variations in the fluorescent intensity and lipid inclusion formation of cells collected at different sampling times illustrate the potential of this bacterium to be useful for cellular lipid production.
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Quantum dot molecules might provide a unique opportunity to study carrier interaction among quantum dots or be useful for quantum cellular automata applications[8, 9].
In addition, the hybrid microfluidic-vacuum platform allows for higher throughput, generates stable concentration gradients, and can be useful for studying cellular behaviors of sensitive cells (mouse NPCs, neurons).
With a growing Spirulina community, the proposed model would not only be useful for studying cellular phenotypes but it could also serve as a platform for "-omics" data integration in order to achieve the beneficial stage of model-driven discovery in Spirulina systems biology [ 8]. S. platensis strain C1 was used in this study.
The effective suppression of vacuolization by GSK-7975A and PD150606 indicate that these compounds could be useful for reducing cellular and tissue damage in acute pancreatitis and should therefore be further tested in in vivo models of this important disease (with the ultimate aim of developing a treatment).
The PLGA sandwiched cell/hydrogel construct was shown to be useful for controlling the cellular microenvironment and cellular behaviors such as growth, migration, proliferation and differentiation.
The transient inter-cellular polymeric linker can be useful for forming 3D cellular and tissue constructs without bulk biomaterials or extensive network of engineered ECM for various applications.
Further studies using this model will be useful for investigating the cellular and molecular mechanisms of DR, including gliotic responses in retinal Muller cells.
scRNA-seq data may be useful for understanding dynamic cellular processes, such as development, reprogramming, differentiation, and disease progression.
This study provides a platform for the development of selective inhibitors of individual PARP family members that will be useful for decoding their cellular functions.
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