Until recently, the technology represented by PCR-based determination of microsatellites only allowed a modest number of polymorphic markers to be used, which limited the resolution of the technique.
A convenience sample was used, which limits the generalisability of the results.
However, stomach irritation may occur when a high dose of borneol is used, which limits the clinical application of borneol as an oral brain-targeting enhancer.
Also in vitro propagation of wild-type ORFV is very restricted and mostly primary ovine or bovine cells are used, which limits the availability of MHC I or cell compartment specific reagents.
7 Due to the strict selection criteria applied, only six RCTs were used, which limited the power of the meta-analysis.
One previous research related with this study is the prioritization of disease miRNAs based on the hypergeometric distribution [ 21], but only the neighbour information of each miRNA was used, which limited its prediction accuracy.
Consequently, small sample sizes must be used, which may limit the representativeness of the findings.
This considerably hinders studying the hydride phase with high spatial resolution, unless a cryogenically cooled liquid nitrogen sample holder is used, which again limits the spatial resolution.
28 While participants were recruited from two geographically distinct locations, convenience sampling was used, which may limit the generalisability of our findings.
In research, specialised finite element analysis (FEA) tools have been used, which is mostly limited to a smeared material model over the entire surface of the panel.
