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A sequential approach to sampling will be used whereby data will be analysed throughout recruitment on an ongoing basis until either the point of data saturation is reached (where no new responses emerge) or a maximum of 20 probands and 20 relatives have been interviewed.
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Consistent with grounded theory methods, theoretical sampling was used whereby data collection was directed by concepts arising in the evolving theory [ 14, 16].
To query the microarray data, a simple form can be used whereby the user can enter a GB number, an array ID s) or a putative function.
Water-based collectors can also be used whereby water to air heat exchanger can be used.
A standard analysis protocol was used whereby raw basecall data was converted to FASTQ sequence files using Off-Line Basecaller 1.9.4 (Illumina) and a custom Perl script.
In order to minimise the amount of missing data for each item, a 'best estimation' method was used whereby respondents with missing data were assigned the item-score of a respondent with a similar age, gender, income, and education level [ 37- 39].
A mixed-methods approach was used whereby quantitative and qualitative data together provided measures of programme impacts as well as essential information regarding conditions that seem to have contributed to or detracted from the success of the programme.
A thematic analysis approach was used, whereby key themes in the data were identified, coded, and analyzed.
A 'store and forward' approach is used whereby images/data acquired at one site are transferred to a remote grader who views these images at a different time.
The intention-to-treat principle will be used for data analysis whereby all participants randomized at the commencement of the trial will remain in the sample for analysis [ 47].
Data are presented to demonstrate how studies with flounder kidney can be used to elucidate cellular mechanisms whereby different classes of toxic pollutants may interact.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com