Sentence examples for be used to downregulate from inspiring English sources

Transcription analysis confirmed that a terminator can be used to downregulate expression of argF and simultaneously improve the transcriptional level of genes in front of argF.

By analysis of l-ornithine production, cell growth, and the relative transcription level of the genes involved in the l-ornithine synthesis pathway, we confirmed that terminators can be used to downregulate argF expression and to improve l-ornithine production.

Since there is 87% homology between mouse and human Grx1, the same shRNA sequence could be used to downregulate Grx1 expression in cells of both murine and human origin (Fig. S1).

On the other hand, the "CRISPRi" system (CRISPR interfering) can be used to downregulate gene expression.

Activated T and B cells express the vitamin D receptor on their surface, which can be used to downregulate IL2 signaling.

For this reason, it is proposed that natural agents can be used to downregulate oncogenic miRNAs and upregulate tumour suppressive miRNAs to restore drug sensitivity.

Multiple biochemical and genetic strategies were used to downregulate early response gene NF-κB, whose activation controls squamous cell cancer-associated pathways.

PTI is analogous to the first line of defense (innate immunity) in vertebrates, which is bypassed or disrupted by pathogen effector molecules that are used to downregulate PTI, making the cell vulnerable to pathogen attack (Nicaise et al. 2009).

Peptide inhibitors have also been used to downregulate translation e.g., BL22, an immunotoxin developed for the treatment of Chronic Lymphocytic Leukemia (CLL) [60], consists of the variable FV fragment of the RFB4 antibody conjugated to the anti-translation peptide PE38.

RNA interference was used to downregulate the expression of Smurf2 in osteoblast cells.

Lentiviral vectors (pGIPZ) expressing shRNAs against ALDH1A1 and ALDH1A3 (Applied Biosystems, Life Technologies) were used to downregulate the expression of these genes.