Since nanostructure designed in this substrate allows sustained drug release, this surface can be used for indications in which enhanced EPC adhesions are desired with simultaneous drug delivery.
Implications and future directions Animal models of disease are important preclinical tools for exploring how drugs can be used for indications other than the diseases they were initially designed to treat.
Two approaches were used for indication of fecal influence.
Currently, risk-assessments with various prognostic and predictive markers are used for indication of systemic treatment, like tumour grade and nodal status for general systemic treatment choice, hormonal receptors for hormonal treatment, and HER2 expression for immunotherapy.
Due to the study size odds ratios of <0.67 or >1.5 have been used for indication of important factors (except in the analysis of factors described in previous literature).
For several conditions, the most widely used drugs are clearly inferior to alternative products and some are used for indications quite different from those in other countries.
This suggests that the drugs are used for indications other than schizophrenia, at least in the elderly group.
In fact, calculating drug coverage using the DDD carries the risk of not accounting for real-life dosing when a drug is used for indications different from its principal indication.
If significant amounts of single dose ciprofloxacin were being used for indications other than chemoprophylaxis, then the ratio of PACT prescriptions to those recorded by GPs would be higher for ciprofloxacin than for rifampicin.
We conducted a survey of pharmacies in the same region and found a surprisingly large quantity of antimicrobial drugs were being used for indications other than trachoma control (6 ).
