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Other experimental measures such as retention indices or drift time, can be used for candidate filtering [205, 207].
The criteria to be used for candidate evaluation and selection should be described.
Findings from these studies can then be used for candidate gene studies to further elaborate on possible drug gene interactions.
The current annotation information can be used for candidate gene discovery, identification of regulatory elements and gene prediction before the full annotation of a pepper genome becomes available.
It has been further argued that to reduce false positives arising from multiple testing, a significance level of 10-4 should be used for candidate gene studies.
The results of the present study have substantially extended comparative knowledge of the field pea and M. truncatula genomes, and such information may be used for candidate gene selection for further application to breeding programs.
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A two step procedure was used for candidate gene identification.
Frozen RCC and normal kidney tissue was used for candidate validation.
The barley and wheat orthologs of the rice FZP/BFL1 gene sequence (Os07g0669500) were used for candidate gene marker development (File S2).
In a study by Rehman and coworkers, this technique was used for candidate biomarker discovery associated with metastasis using both patient sample as well as prostate cancer cell lines [ 57].
As a result, a total of 33 putatively genes encoded sequences encompassed in these two regions were used for candidate gene detection by the GO annotation (Table 6) (Figs. 7 and 8).
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