Sentence examples for be unstructured in the from inspiring English sources
The short (6-residue) helix III has been shown to be unstructured in the intermediate ensemble and does not dock onto the developing hydrophobic core until after the rate-limiting transition state has been traversed.
The extended conformation of Scc21 181 clearly depends on its contacts with the surrounding Scc4; it is likely to be unstructured in the absence of its partner.
These residues possibly act as linkers connecting domains of topoisomerase I that interact with opposite sides of the DNA; they may be unstructured in the apoprotein and become ordered upon binding DNA.
Twitter communication is unstructured in the sense that every user can send a message to any other user.
Experimentally, it is known that the NLS polypeptide is unstructured in the NF-κB complex with DNA but it forms an extended helical structure with the NLS (residues 301 304) between the two helices in the NF-κB/IκBα complex.
The accessory motif PAR is unstructured in the absence of DNA and assumes a more ordered conformation when bound to DNA [16].
Recent crystal structure of PcrH showed that it is also a dimer, although the dimer interactions are made through the convex side of the TPR fold instead of the N-terminal region and TPR 1. Also, there are no additional helices N-terminal to TPR 1 in PcrH as the N-terminal 20 residues are disordered and residues 21 31 are unstructured in the crystal structure [17].
Sir3 BAH also contacts the H2A/H2B acidic patch using the loop 1 region that is unstructured in the absence of the NCP.
Φ-Values close to zero indicate that the transition state (or intermediate) is unstructured in the region of the amino acid substitution, while higher Φ-values indicate that the region is structured in the transition state (or intermediate) [161,162].
