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Interestingly, during the 48 h treatment time the dual HER2/EGFR inhibitor lapatinib, currently in use for second-line therapy of herceptin-resistant ER+EGFR+HER2+ breast cancers, did not reduce the pLB subpopulation, consistent with the fact that HER2– tumors (like pLB) tend to be unresponsive to this drug [ 19].
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Patients with tumors expressing a high level of HOXB13 were more likely to be unresponsive to the therapy, suggesting that this gene is involved in tamoxifen resistance.
They should be unresponsive to the stimulus.
Patients who are unresponsive to this treatment will proceed to the last step of the stepped care program (4) Pharmacotherapy and/or specialized mental health care.
In the same system, EGF at 20 and 50 ng ml−l stimulated LNCaP cell proliferation but not that of PC3 cells, which are unresponsive to this growth factor (El Sheikh et al, 2004).
People will be unresponsive to him at their peril".
Blood constituents were unresponsive to the saline vehicle.
He was unresponsive to the group's entreaties.
Local government is unresponsive to the needs of the people.
EQ-VAS proved to be unresponsive to change from baseline.
These membranes may also be unresponsive to physiological stimuli.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com