Sentence examples for be uniquely required for from inspiring English sources
While the view 15 years ago conveyed the idea that a given signalling cascade would be uniquely required for a given response, it has now emerged that several alternative pathways, although distinct from each other by their components, can substitute for one another to activate a given biological response.
Furthermore, we discovered that Bap1 is uniquely required for the maintenance of the mechanical strength of the pellicle over time and contributes to the hydrophobicity of the pellicle.
Here, using KO myoblasts, we demonstrated that Rb, but not p107 plus p130, is uniquely required for cell cycle exit during terminal differentiation of primary myoblasts.
We also observed that the domains of HIV-1 Vif that are uniquely required for its functional interaction with full-length A3F are also required for the degradation of the C-CDD of A3F; in contrast, those Vif domains that are uniquely required for functional interaction with A3G are not required for the degradation of the C-CDD of A3F.
As a potential basis for this observation, it was suggested that Rb inactivation is uniquely required for cancer progression because only after its loss can tumor cells escape senescence under oncogenic stress [39].
GRP94 is highly conserved in vertebrates but not in yeast and has been well documented to be inducible by a variety of metabolic stresses, suggesting that it is uniquely required for functions in vertebrates not shared by yeast.
(C ) Dual palmitoylation is uniquely required for LIMK1 T508 phosphorylation in neurons.
Furthermore, Smc3 acetylation by Eco1 was uniquely required for S-phase cohesion, but not for DI cohesion.
Thus, not only that GRP78 function cannot be compensated by GRP94, GRP78 is uniquely required for Purkinje cell survival.
