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Even though the Warburg effect is seen in many cancer forms, ccRCC seems to be uniquely dependent on glycolysis, showing a reduction of most other energy-generating metabolic processes.
Moreover, GSK3 β, a downstream target of Akt which is said to be involved in oxidative stress-mediated cell death, is observed to be uniquely dependent on Akt phosphorylation at Ser473.
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Basal cell carcinomas are uniquely dependent on the inappropriate activation of the Hedgehog pathway.
The governor, who is legally blind, has been uniquely dependent on his staff, especially on Mr. O'Byrne, his confidant and alter ego.
Since the performance of a specific semiconductor device is uniquely dependent on the vital features like scattering, mobility, temperature, conductivity etc.
Puerto Rico's food stamps program is uniquely dependent on periodic help from Congress, though the island does not have a voting representative in either the House or Senate, or a say in presidential elections.
Two types of metrics are discussed: those that are universal in nature and scene or landscape feature-independent and those that are uniquely dependent on scenic structure, meteorological conditions, and observer illumination geometry.
Dr Shepard said: "Condors are uniquely dependent on sources of lift in order to travel.
Twitter is uniquely dependent on and responsible for the long-term health and value of the platform.
The ability of cells to undergo HRR is uniquely dependent on RAD51, which is involved in the search for DNA homology and in the strand-pairing stages [3].
The identification of biologically meaningful factors is uniquely dependent on the data and cannot be guaranteed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com