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As a result, anti-predator behaviors may not be under selection in cattle, and may actually be selected against (see below).
Therefore, these genes may be under selection in natural populations.
Several genes found to have high pN/pS are suggested to be under selection in other species, including GB52930 (the honey bee ortholog of Drosophila gene armitage) which appears to be under selection in Drosophila simulans.
Also, several life history traits have been shown to be under selection in these species [ 16- 21].
Intra-species polymorphism analysis identified 81 loci as likely to be under selection in the sequenced genomes.
Thus silent sites in nucleotide binding genes are likely to be under selection in both unicellular and multicellular eukaryotes.
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Dr. Pritchard's test identified 206 regions of the genome that are under selection in the Yorubans, 185 regions in East Asians and 188 in Europeans.
This supports the previous findings that the functional variant of ADH cluster region is under selection in the east Asian populations3,34.
Derived alleles of pigmentation markers that are under selection in Europeans are present in eastern and western Scythians, including individuals who are homozygous for the derived alleles at selected SNPs in the HERC2, SLC24A5 or SLC45A2 (ref. 43, 44, 45).
The ancestral alleles at ADH1B rs3811801 and rs1229984 are nearly fixed in the Scythian dataset, as they are in modern Europeans (the derived alleles, which confer some resistance to alcoholism, are under selection in East Asians46,47).
Dr. Pritchard's team found that several genes associated with embryonic development of the bones had been under selection in East Asians and Europeans, and these could be another sign of the forager-to-farmer transition, Dr. Klein said.
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