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For example, with the P-value cutoff of 1 × 10−4, proximal enhancers were more likely to be under positive selective pressure than tele-enhancers 2.5tele-enhancers 2.5% tele-enhancers evolved under proximal selection (binomiandtest P-value = 4 × 1.5%, proximal vs. tele-enhancers).
As long as indirect benefits from such arrangements outweigh any costs to individuals, such as loss of personal centrality in either centralized or decentralized groups, the mechanisms that favor such arrangement will be under positive selective pressure.
Most of the gene families identified to be under positive selective pressure were just sequence pairs.
Most of the gene families we found have molecular functions that are known to be under positive selective pressure.
Some codons were found to be under positive selective pressure but it failed to be related to the therapy.
Codons 157 (P03), 182 and 440 (P42), 62 and 404 (P44) were found to be under positive selective pressure but it failed to be related to the therapy.
Similar(46)
These analyses confirmed that several of the amino acid positions in the AL9 epitope (83, 85, 87 and 91), were under positive selective pressure, presumably caused by the HLA-A2-restricted CTL response (Figure 4).
Recently, its homologue in B. dolosa, FixK, was shown to be under the control of an oxygen-sensing two component system, FixLJ which is under positive selective pressure during CF chronic infection44.
Therefore, to determine if there were small regions of the protein that were under positive selective pressure, we examined the dN/dS ratio by the Li-Kimura method in overlapping windows of 10 codons.
They show that long-wavelength sensitive opsins are highly duplicated in this fish and several sites are under positive selective pressure.
This conservation of the isoforms across species suggests they have been under positive selective pressure and hence have distinct roles required for normal development.
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