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The unchanged or increased abundances of miR172 target mRNAs in the miR172b over-expression plants is reminiscent of observations made in Arabidopsis [ 13, 21] where there is evidence that miR172 acts to repress translation and for transcription of the AP2-like genes to be under negative feedback regulation via their protein products.
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It has been previously reported that mammalian ODC protein has a very short half-life; its control is under negative feedback regulation by the polyamines, and its degradation is dependent on 26S proteasome complex (Hascilowicz et al. 2002).
FacX induces WUS expression, but is itself under negative feedback regulation by WUS [14].
All steroidal hormones in the blood of humans are under the negative feedback control of hormones that are secreted by the anterior aspect of the pituitary gland.
Raldh2 is under the negative feedback regulation of RA.
My hunch (and hope) is it will be negative feedback.
We had hypothesized that bone formation to bridge the fracture gap would be under a negative-feedback control system.
A possible explanation for this paradox is that aberrant signaling by a mutated gene can be counteracted by negative feedback loops that under particular circumstances may account for most of the transcriptional changes observed at the steady-state level.
Also be ready for negative feedback.
While Stascavage knew the piece would be "controversial," the negative feedback completely exceeded his expectations. .
This may be due to negative feedback.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com