Sentence examples for be under functional constraint from inspiring English sources

This feature may be even more critical in compact genomes such as D. melanogaster, where much of the genome appears to be under functional constraint and it is therefore more likely for functional elements to be located near each other [18].

Thus, XXyac-R12DG2.2 is likely to be under functional constraint.

These conserved sequences are expected to be under functional constraint.

Therefore, the longer the BLS value the more likely it will be under functional constraint.

Secondly, it is likely that EST-SSRs within non-coding regions are more variable than those found in coding regions, as they are less likely to be under functional constraint.

Conservatively speaking, the substitution rate in the GC42 stem regions has been significantly reduced from the genome-wide mutation rate, thus GC42 is believed to be under functional constraint.

Therefore, these clusters are likely to be under functional constraints.

It has been supposed that this sequences have the potential to form strong secondary structures suggesting that the region may be under functional constraints.

The PGL genes had much lower nucleotide diversity, which was especially evident in SDHB, suggesting that the SDHB gene product might be under functional constraints that preclude the accumulation of variants.

The conservation level, coverage of SNV, GC content, and overlap with previously reported regulatory signatures as well as DAF analysis support that the CNSs identified are under functional constraint and may have regulatory functions.

The optimal value for ω was < 1 in all pairwise comparisons (Table 1) suggesting that the transferred genes may have been under functional constraint for some period of time before they lost function.